CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain

Circular RNAs are non-coding RNAs that are enriched in the CNS, but their role in chronic pain is not known. Here the authors show that CircAnks1a in dorsal horn neurons contributes to pain-like hypersensitivity in a rodent model of neuropathic pain, via a VEGF mechanism.

Bibliographic Details
Main Authors: Su-Bo Zhang, Su-Yan Lin, Meng Liu, Cui-Cui Liu, Huan-Huan Ding, Yang Sun, Chao Ma, Rui-Xian Guo, You-You Lv, Shao-Ling Wu, Ting Xu, Wen-Jun Xin
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12049-0