Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration

<p>Abstract</p> <p>Background</p> <p>The invasive potential of cancer cells is usually assessed <it>in vitro </it>using Matrigel as a surrogate basement membrane. Yet cancer cell interaction with collagen I matrices is critical, particularly for the peritone...

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Bibliographic Details
Main Authors: Brown Theodore J, Sodek Katharine L, Ringuette Maurice J
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/223