Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle

Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle

Fatty acids are the primary fuel source for skeletal muscle during most of our daily activities, and impaired fatty acid oxidation (FAO) is associated with insulin resistance. We have developed a mouse model of impaired FAO by deleting carnitine palmitoyltransferase-1b specifically in skeletal muscl...

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Bibliographic Details
Main Authors: Bolormaa Vandanmagsar, Jaycob D. Warfel, Shawna E. Wicks, Sujoy Ghosh, J. Michael Salbaum, David Burk, Olga S. Dubuisson, Tamra M. Mendoza, Jingying Zhang, Robert C. Noland, Randall L. Mynatt
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716305010

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http://www.sciencedirect.com/science/article/pii/S2211124716305010

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