Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro

Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro

Many studies have demonstrated that berberine inhibited the cell migration and invasion in human cancer cell lines. However, the exact molecular mechanism of berberine inhibiting the cell migration and invasion of human melanoma A375.S2 and A375.S2/PLX (PLX4032 induced resistant A375.S2) skin cancer...

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Bibliographic Details
Main Authors: Jia-Fang Liu, Kuang Chi Lai, Shu-Fen Peng, Pornsuda Maraming, Yi-Ping Huang, An-Cheng Huang, Fu-Shin Chueh, Wen-Wen Huang, Jing-Gung Chung
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
berberine
human melanoma A375.S2
PLX4032
migration
invasion
Online Access:http://www.mdpi.com/1420-3049/23/8/2019

Internet

http://www.mdpi.com/1420-3049/23/8/2019

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