CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

Summary: CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these cells. In this study, we show that CD137 signaling, specifically in intestinal CD11b−CD103+ dendritic cells (DCs), restricts acute coliti...

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Bibliographic Details
Main Authors: Jing Jin, In-Hyuk Jung, Shin Hye Moon, Sejin Jeon, Se-Jin Jeong, Seong-Keun Sonn, Seungwoon Seo, Mi-Ni Lee, Eun Ju Song, Hyae Yon Kweon, Sinai Kim, Tae Kyeong Kim, Juyang Kim, Hong Rae Cho, Jae-Hoon Choi, Byungsuk Kwon, Goo Taeg Oh
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302849

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http://www.sciencedirect.com/science/article/pii/S2211124720302849

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