Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients

DEFA1/DEFA3, genes encoding human neutrophil peptides (HNP) 1–3, display wide-ranging copy number variations (CNVs) and is functionally associated with innate immunity and infections. To identify potential associations between DEFA1/DEFA3 CNV and hospital-acquired infections (HAIs), we enrolled 106...

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Bibliographic Details
Main Authors: Jialian Zhao, Qiang Gu, Lifeng Wang, Weize Xu, Lihua Chu, Ya Wang, Zhongwang Li, Shuijing Wu, Jianguo Xu, Zhiyong Hu, Qiang Shu, Xiangming Fang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/2152650

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http://dx.doi.org/10.1155/2018/2152650

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