The Combined Use of Gentamicin and Silver Nitrate in Bone Cement for a Synergistic and Extended Antibiotic Action against Gram-Positive and Gram-Negative Bacteria

Using bone cement as a carrier, gentamicin was for years the default drug to locally treat orthopedic infections but has lost favor due to increasing bacterial resistance to this drug. The objective of this study was to investigate the effect of combining gentamicin with silver nitrate in bone cemen...

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Bibliographic Details
Main Authors: John Jackson, Joey Lo, Eric Hsu, Helen M. Burt, Ali Shademani, Dirk Lange
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/14/12/3413