Single-Cell Protein and RNA Expression Analysis of Mononuclear Phagocytes in Intestinal Mucosa and Mesenteric Lymph Nodes of Ulcerative Colitis and Crohn’s Disease Patients

Single-Cell Protein and RNA Expression Analysis of Mononuclear Phagocytes in Intestinal Mucosa and Mesenteric Lymph Nodes of Ulcerative Colitis and Crohn’s Disease Patients

Inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are driven by an abnormal immune response to commensal microbiota in genetically susceptible hosts. In addition to epithelial and stromal cells, innate and adaptive immune systems are both involved in...

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Bibliographic Details
Main Authors: Laurence Chapuy, Marika Sarfati
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
mononuclear phagocytes
inflammatory bowel disease
Crohn’s disease
ulcerative colitis
single cell RNA sequencing
flow cytometry
Online Access:https://www.mdpi.com/2073-4409/9/4/813

Internet

https://www.mdpi.com/2073-4409/9/4/813

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