Leveraging TCGA gene expression data to build predictive models for cancer drug response

Abstract Background Machine learning has been utilized to predict cancer drug response from multi-omics data generated from sensitivities of cancer cell lines to different therapeutic compounds. Here, we build machine learning models using gene expression data from patients’ primary tumor tissues to...

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Bibliographic Details
Main Authors: Evan A. Clayton, Toyya A. Pujol, John F. McDonald, Peng Qiu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03690-4

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