Cellular processing of myocilin.

Myocilin (MYOC) is a gene linked directly to juvenile- and adult-onset open angle glaucoma. Mutations including Pro370Leu (P370L) and Gln368stop (Q368X) have been identified in patients. In the present study, we investigated the processing of myocilin in human trabecular meshwork (TM) cells as well...

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Bibliographic Details
Main Authors: Ye Qiu, Xiang Shen, Rajalekshmy Shyam, Beatrice Y J T Yue, Hongyu Ying
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986080?pdf=render