A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.

A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.

<h4>Objectives</h4>Elevated matrix metalloproteinase-2 (MMP-2) tissue levels have been associated with ascending thoracic aortic aneurysm (aTAA). As MMP-2 activation is controlled by interactions among matrix metalloproteinase-14 (MMP-14), a tissue inhibitor of metalloproteinases-2 (TIMP...

Full description

Bibliographic Details
Main Authors: Ramona Schmitt, Anke Tscheuschler, Philipp Laschinski, Xenia Uffelmann, Philipp Discher, Jana Fuchs, Maximilian Kreibich, Remi Peyronnet, Fabian A Kari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212859

Internet

https://doi.org/10.1371/journal.pone.0212859

Similar Items