Distribution of peripheral PrP(Sc) in sheep with naturally acquired scrapie.

Accumulation of prion protein (PrPSc) in the central nervous system is the hallmark of transmissible spongiform encephalopathies. However, in some of these diseases such as scrapie or chronic wasting disease, the PrPSc can also accumulate in other tissues, particularly in the lymphoreticular system....

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Bibliographic Details
Main Authors: María Carmen Garza, Marta Monzón, Belén Marín, Juan José Badiola, Eva Monleón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020850?pdf=render