Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins

Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins

Oxidized cholesterol is present in significant quantities in the typical Western diet. When ingested, oxidized cholesterol is absorbed by the small intestine and incorporated into both chylomicrons and LDL, resulting in LDL that is more susceptible to further oxidation. Feeding studies in animal mod...

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Bibliographic Details
Main Authors: Ilona Staprans, Xian-Mang Pan, Joseph H. Rapp, Arthur H. Moser, Kenneth R. Feingold
Format: Article
Language:English
Published: Elsevier 2006-11-01
Series:Journal of Lipid Research
Subjects:
oxidized lipoproteins
diet
cholesterol absorption
α-epoxy cholesterol
7-keto cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520433929

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http://www.sciencedirect.com/science/article/pii/S0022227520433929

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