Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patients

Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patients

Abstract Background BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. Methods We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI. We identified additive interactions betwee...

Full description

Bibliographic Details
Main Authors: Agnieszka H. Ludwig-Słomczyńska, Michał T. Seweryn, Przemysław Kapusta, Ewelina Pitera, Samuel K. Handelman, Urszula Mantaj, Katarzyna Cyganek, Paweł Gutaj, Łucja Dobrucka, Ewa Wender-Ożegowska, Maciej T. Małecki, Paweł P. Wołkow
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Medical Genomics
Subjects:
Obesity
Mitochondria
Mitochondrial-nuclear interactions
GWAS
Online Access:http://link.springer.com/article/10.1186/s12920-020-00752-7

Internet

http://link.springer.com/article/10.1186/s12920-020-00752-7

Similar Items