A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells.

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells.

Amyotrophic lateral sclerosis is a progressive disease characterized by the loss of upper and lower motor neurons, leading to paralysis of voluntary muscles. About 10% of all ALS cases are familial (fALS), among which 15-20% are linked to Cu/Zn superoxide dismutase (SOD1) mutations, usually inherite...

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Bibliographic Details
Main Authors: Ying Li, Umamahesw Balasubramanian, Devon Cohen, Ping-Wu Zhang, Elizabeth Mosmiller, Rita Sattler, Nicholas J Maragakis, Jeffrey D Rothstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0118266

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https://doi.org/10.1371/journal.pone.0118266

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