Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes

Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes

Abstract High-charge, high-energy ion particle (HZE) radiations are extraterrestrial in origin and characterized by high linear energy transfer (high-LET), which causes more severe cell damage than low-LET radiations like γ-rays or photons. High-LET radiation poses potential cancer risks for astrona...

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Bibliographic Details
Main Authors: Liang-Hao Ding, Yongjia Yu, Elijah F. Edmondson, Michael. M. Weil, Laurentiu M. Pop, Maureen McCarthy, Robert L. Ullrich, Michael D. Story
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93467-3

Internet

https://doi.org/10.1038/s41598-021-93467-3

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