Engeletin ameliorates pulmonary fibrosis through endoplasmic reticulum stress depending on lnc949-mediated TGF-β1-Smad2/3 and JNK signalling pathways

Engeletin ameliorates pulmonary fibrosis through endoplasmic reticulum stress depending on lnc949-mediated TGF-β1-Smad2/3 and JNK signalling pathways

Context Pulmonary fibrosis (PF) is a highly heterogeneous and lethal pathological process having no effective drug. Engeletin exerts multiple biological activities including anti-inflammatory and lung repair. Whether engeletin has therapeutic effects on PF remains unclear. Objective Examining effect...

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Bibliographic Details
Main Authors: Jinjin Zhang, Xiaoqing Chen, Hongbin Chen, Rongrong Li, Pan Xu, Changjun Lv, Bo Liu, Xiaodong Song
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
pf
lncrna
rna sequence
perk-atf4 signalling pathway
er stress
Online Access:http://dx.doi.org/10.1080/13880209.2020.1834590

Internet

http://dx.doi.org/10.1080/13880209.2020.1834590

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