Zearalenone Induces Apoptosis and Cytoprotective Autophagy in Chicken Granulosa Cells by PI3K-AKT-mTOR and MAPK Signaling Pathways

Zearalenone Induces Apoptosis and Cytoprotective Autophagy in Chicken Granulosa Cells by PI3K-AKT-mTOR and MAPK Signaling Pathways

Zearalenone (ZEA) is a nonsteroidal estrogenic mycotoxin found in several food commodities worldwide. ZEA causes reproductive disorders, genotoxicity, and testicular toxicity in animals. However, little is known about the functions of apoptosis and autophagy after exposure to ZEA in granulosa cells....

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Bibliographic Details
Main Authors: Yifeng Zhu, Heng Wang, Jianping Wang, Shunshun Han, Yao Zhang, Menggen Ma, Qing Zhu, Keying Zhang, Huadong Yin
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Toxins
Subjects:
zearalenone
apoptosis
autophagy
granulosa cells
PI3K-AKT-mTOR
MAPK
Online Access:https://www.mdpi.com/2072-6651/13/3/199

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https://www.mdpi.com/2072-6651/13/3/199

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