IscR regulation of capsular polysaccharide biosynthesis and iron-acquisition systems in Klebsiella pneumoniae CG43.

IscR, an Fe-S cluster-containing transcriptional factor, regulates genes involved in various cellular processes. In response to environmental stimuli such as oxidative stress and iron levels, IscR switches between its holo and apo forms to regulate various targets. IscR binding sequences are classif...

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Bibliographic Details
Main Authors: Chien-Chen Wu, Chien-Kuo Wang, Yu-Ching Chen, Tien-Huang Lin, Tzyy-Rong Jinn, Ching-Ting Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169559?pdf=render