Design, Synthesis and Antibacterial Activity of Coumarin-1,2,3-triazole Hybrids Obtained from Natural Furocoumarin Peucedanin

Design, Synthesis and Antibacterial Activity of Coumarin-1,2,3-triazole Hybrids Obtained from Natural Furocoumarin Peucedanin

Synthesis of 1,2,3-triazole-substituted coumarins and also 1,2,3-triazolyl or 1,2,3-triazolylalk-1-inyl-linked coumarin-2,3-furocoumarin hybrids was performed by employing the cross-coupling and copper catalyzed azide-alkyne cycloaddition reaction approaches. The synthesized compounds were evaluated...

Full description

Bibliographic Details
Main Authors: Alla V. Lipeeva, Danila O. Zakharov, Liubov G. Burova, Tatyana S. Frolova, Dmitry S. Baev, Ilia V. Shirokikh, Alexander N. Evstropov, Olga I. Sinitsyna, Tatyana G. Tolsikova, Elvira E. Shults
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
coumarin
furocoumarin
Sonogashira coupling
CuAAC reaction
antibacterial activity
Online Access:https://www.mdpi.com/1420-3049/24/11/2126

Internet

https://www.mdpi.com/1420-3049/24/11/2126

Similar Items