Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency

Summary: Naive and primed human pluripotent stem cells (hPSCs) have provided useful insights into the regulation of pluripotency. However, the molecular mechanisms regulating naive conversion remain elusive. Here, we report intermediate naive conversion induced by overexpressing nuclear receptor 5A1...

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Bibliographic Details
Main Authors: Kaori Yamauchi, Tatsuhiko Ikeda, Mihoko Hosokawa, Norio Nakatsuji, Eihachiro Kawase, Shinichiro Chuma, Kouichi Hasegawa, Hirofumi Suemori
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671120300333