MEIS2C and MEIS2D promote tumor progression via Wnt/β-catenin and hippo/YAP signaling in hepatocellular carcinoma

MEIS2C and MEIS2D promote tumor progression via Wnt/β-catenin and hippo/YAP signaling in hepatocellular carcinoma

Abstract Background MEIS2 has been identified as one of the key transcription factors in the gene regulatory network in the development and pathogenesis of human cancers. Our study aims to identify the regulatory mechanisms of MEIS2 in hepatocellular carcinoma (HCC), which could be targeted to devel...

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Bibliographic Details
Main Authors: Lei Guan, Ting Li, Nanping Ai, Wei Wang, Bing He, Yanxia Bai, Zhaocai Yu, Mingyue Li, Shanshan Dong, Qingge Zhu, Xiao Xiao Ding, Shiming Zhang, Ming li, Guangbo Tang, Xiaochun Xia, Jing Zhao, Song lin, Shi yao, Lei zhang, Geng chen, Fang-E Liu, Xinyuan Li, Huqin Zhang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
HCC
MEIS2
Alternative splicing
Wnt
Hippo
CDC-73
Online Access:http://link.springer.com/article/10.1186/s13046-019-1417-3

Internet

http://link.springer.com/article/10.1186/s13046-019-1417-3

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