Estimating the basic reproduction number of a pathogen in a single host when only a single founder successfully infects.

If viruses or other pathogens infect a single host, the outcome of infection may depend on the initial basic reproduction number R0, the expected number of host cells infected by a single infected cell. This article shows that sometimes, phylogenetic models can estimate the initial R0, using only se...

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Bibliographic Details
Main Authors: Vruj Patel, John L Spouge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227127