Ablation of p75NTR signaling strengthens gamma–theta rhythm interaction and counteracts Aβ-induced degradation of neuronal dynamics in mouse hippocampus in vitro

Abstract Gamma and theta brain rhythms play important roles in cognition and their interaction can affect gamma oscillation features. Hippocampal theta oscillations depend on cholinergic and GABAergic input from the medial septum-diagonal band of Broca. These projecting neurons undergo degeneration...

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Bibliographic Details
Main Authors: Yuniesky Andrade-Talavera, Hugo Balleza-Tapia, Pablo Dolz-Gaitón, Gefei Chen, Jan Johansson, André Fisahn
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01332-8