Decoupling Epigenetic and Genetic Effects through Systematic Analysis of Gene Position

Classic “position-effect” experiments repositioned genes near telomeres to demonstrate that the epigenetic landscape can dramatically alter gene expression. Here, we show that systematic gene knockout collections provide an exceptional resource for interrogating position effects, not only near telo...

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Bibliographic Details
Main Authors: Menzies Chen, Katherine Licon, Rei Otsuka, Lorraine Pillus, Trey Ideker
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004275