Naringin increases osteoprotegerin expression in fibroblasts from periprosthetic membrane by the Wnt/β-catenin signaling pathway

Naringin increases osteoprotegerin expression in fibroblasts from periprosthetic membrane by the Wnt/β-catenin signaling pathway

Abstract Background The osteoclast bone resorption is critical in aseptic loosening after joint replacement. The balance between activator of nuclear factor kappa B ligand (RANKL) and osteoprotegerin (OPG) is considered to play a central role in osteoclast maturation. Fibroblasts from the periprosth...

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Bibliographic Details
Main Authors: Chao Yang, Wei Liu, Xianlong Zhang, Bingfang Zeng, Yebin Qian
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Naringin
Osteoprotegerin
Wnt/β-catenin
Fibroblasts
Aseptic loosening
Online Access:https://doi.org/10.1186/s13018-020-02145-z

Internet

https://doi.org/10.1186/s13018-020-02145-z

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