The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response.

BACKGROUND: Many of the PE/PPE proteins are either surface localized or secreted outside and are thought to be a source of antigenic variation in the host. The exact role of these proteins are still elusive. We previously reported that the PPE41 protein induces high B cell response in TB patients. T...

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Bibliographic Details
Main Authors: Smanla Tundup, Niteen Pathak, M Ramanadham, Sangita Mukhopadhyay, K J R Murthy, Nasreen Z Ehtesham, Seyed E Hasnain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2570489?pdf=render