An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis

An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis

<p>Abstract</p> <p>Background</p> <p>Despite entering complete remission after primary treatment, a substantial proportion of patients with early stage breast cancer will develop metastases. Prediction of such an outcome remains challenging despite the clinical use of s...

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Bibliographic Details
Main Authors: Bonnet Françoise, Guedj Mickael, Jones Natalie, Sfar Sana, Brouste Véronique, Elarouci Nabila, Banneau Guillaume, Orsetti Béatrice, Primois Charlotte, de Lara Christine Tunon, Debled Marc, de Mascarel Isabelle, Theillet Charles, Sévenet Nicolas, de Reynies Aurélien, MacGrogan Gaëtan, Longy Michel
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Medical Genomics
Subjects:
Breast cancer
Array CGH
Prognosis
Genetic instability
Online Access:http://www.biomedcentral.com/1755-8794/5/54

Internet

http://www.biomedcentral.com/1755-8794/5/54

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