Demographic history and selection at HLA loci in Native Americans.

The American continent was the last to be occupied by modern humans, and native populations bear the marks of recent expansions, bottlenecks, natural selection, and population substructure. Here we investigate how this demographic history has shaped genetic variation at the strongly selected HLA loc...

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Bibliographic Details
Main Authors: Richard M Single, Diogo Meyer, Kelly Nunes, Rodrigo Santos Francisco, Tábita Hünemeier, Martin Maiers, Carolyn K Hurley, Gabriel Bedoya, Carla Gallo, Ana Magdalena Hurtado, Elena Llop, Maria Luiza Petzl-Erler, Giovanni Poletti, Francisco Rothhammer, Luiza Tsuneto, William Klitz, Andrés Ruiz-Linares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241282