Down-Regulation of MicroRNA-137 Improves High Glucose-Induced Oxidative Stress Injury in Human Umbilical Vein Endothelial Cells by Up-Regulation of AMPKα1

Down-Regulation of MicroRNA-137 Improves High Glucose-Induced Oxidative Stress Injury in Human Umbilical Vein Endothelial Cells by Up-Regulation of AMPKα1

Background/Aims: To investigate the effects of miR-137 on high glucose (HG)-induced vascular injury, and to establish the mechanism underlying these effects. Methods: Human umbilical vein endothelial cells (HUVECs) were transfected with miR-137 inhibitor or mimic, and then treated with normal or hig...

Full description

Bibliographic Details
Main Authors: Jie Li, Junfeng Li, Tingting Wei, Junhua Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
AMPKα1
Oxidative stress
MicroRNA-137
HUVEC
High glucose
Online Access:http://prod.karger.com/Article/FullText/447795

Internet

http://prod.karger.com/Article/FullText/447795

Similar Items