A Boolean model of the gene regulatory network underlying Mammalian cortical area development.

The cerebral cortex is divided into many functionally distinct areas. The emergence of these areas during neural development is dependent on the expression patterns of several genes. Along the anterior-posterior axis, gradients of Fgf8, Emx2, Pax6, Coup-tfi, and Sp8 play a particularly strong role i...

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Bibliographic Details
Main Authors: Clare E Giacomantonio, Geoffrey J Goodhill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20862356/?tool=EBI