Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies

Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies

Background: Cardiac development is a dynamic process both temporally and spatially. These complex processes are often disturbed and lead to congenital cardiac anomalies that affect approximately 1% of live births. Disease-causing variants in several genetic loci lead to cardiac anomalies, with varia...

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Bibliographic Details
Main Authors: Olivia Moumne, Rajib Chowdhurry, Cassandra Doll, Natalia Pereira, Mustafa Hashimi, Tabor Grindrod, James J. Dollar, Alberto Riva, Hideko Kasahara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac anomaly
gestational hypoxia
genetic mutation
mouse models
nkx2-5
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00100/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00100/full

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