RECQL1 Plays an Important Role in the Development of Tongue Squamous Cell Carcinoma

Background/Aims: RECQL1, a member of the human RECQ helicase family, participates in DNA repair. Recent reports showed that RECQL1 silencing in cancer cells resulted in mitotic catastrophe, which prevented tumor growth in murine models. However, its therapeutic potential has never been examined in t...

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Bibliographic Details
Main Authors: Jiang Tao, Suxiong Tao, Junli Han, Zhuojun Zhou, Xiaoping Zhang, Haining Wang, Rongjing Chen, Fang Ji, Yaqin Zhu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/358721