P2Y12 shRNA normalizes inflammatory dysfunctional hepatic glucokinase activity in type 2 diabetic rats

The celiac ganglion projects its postganglionic (including purinergic) fibers to the liver. P2Y12 receptor is one of the P2Y family members. We found that the expression levels of P2Y12 receptor in both celiac ganglia and liver were increased in type 2 diabetes mellitus (T2DM) rats which also displa...

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Bibliographic Details
Main Authors: Lin Li, Jingjian Yang, Baoe Liu, Yuting Zou, Minghao Sun, Zijing Li, Runan Yang, Xiumei Xu, Lifang Zou, Guilin Li, Shuangmei Liu, Guodong Li, Shangdong Liang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220309963