Low-dose amikacin in the treatment of Multidrug-resistant Tuberculosis (MDR-TB)

Abstract Background The World Health Organization recommends intravenous amikacin for the treatment of MDR-TB at a dose of 15 mg/kg. However, higher doses are associated with significant toxicity. Methods Patients with MDR-TB treated at our institution receive amikacin at 8–10 mg/kg, with dose adjus...

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Bibliographic Details
Main Authors: Natasha F. Sabur, Mantaj S. Brar, Lisa Wu, Sarah K. Brode
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Infectious Diseases
Subjects:
Online Access:https://doi.org/10.1186/s12879-021-05947-6