An Intronic Alu Element Attenuates the Transcription of a Long Non-coding RNA in Human Cell Lines

An Intronic Alu Element Attenuates the Transcription of a Long Non-coding RNA in Human Cell Lines

Alu elements are primate-specific repeats and represent the most abundant type of transposable elements (TE) in the human genome. Genome-wide analysis of the enrichment of histone post-translational modifications suggests that human Alu sequences could function as transcriptional enhancers; however,...

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Bibliographic Details
Main Authors: Rosario Pérez-Molina, Rodrigo G. Arzate-Mejía, Erandi Ayala-Ortega, Georgina Guerrero, Karin Meier, Fernando Suaste-Olmos, Félix Recillas-Targa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Genetics
Subjects:
repeat sequences
Alu elements
intragenic enhancer
long intergenic non-coding RNAs
transcription attenuation
transposable elements
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00928/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00928/full

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