GSK-3β, a pivotal kinase in Alzheimer disease

GSK-3β, a pivotal kinase in Alzheimer disease

Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of AD is considered to be multifactorial as only a negligible percentage of cases have a familial or genetic origin. Glycogen synthase kinase-3 (GSK-3) is regarded as a critical molecular link between the two histop...

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Bibliographic Details
Main Authors: Maria eLLorens-Martin, Jeronimo eJurado, Felix eHernandez, Jesus eAvila
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer Disease
tau Proteins
neurodegeneration
kinase
GSK3b
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00046/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00046/full

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