Angiotensin-induced abdominal aortic aneurysms in hypercholesterolemic mice: role of serum cholesterol and temporal effects of exposure.

Understanding variations in size and pattern of development of angiotensin II (Ang II)-induced abdominal aortic aneurysms (AAA) may inform translational research strategies. Thus, we sought insight into the temporal evolution of AAA in apolipoprotein (apo)E(-/-) mice.A cohort of mice underwent a 4-w...

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Bibliographic Details
Main Authors: Petra A Prins, Michael F Hill, David Airey, Sam Nwosu, Prudhvidhar R Perati, Hagai Tavori, Macrae F Linton, Valentina Kon, Sergio Fazio, Uchechukwu K Sampson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900396?pdf=render