Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors, including Gata4, Mef2c, and Tbx5; however, this process is inefficient under serum-based culture conditions, in which conversion of partially reprogrammed cells into full...

Full description

Bibliographic Details
Main Authors: Hiroyuki Yamakawa, Naoto Muraoka, Kazutaka Miyamoto, Taketaro Sadahiro, Mari Isomi, Sho Haginiwa, Hidenori Kojima, Tomohiko Umei, Mizuha Akiyama, Yuki Kuishi, Junko Kurokawa, Tetsushi Furukawa, Keiichi Fukuda, Masaki Ieda
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003161

Internet

http://www.sciencedirect.com/science/article/pii/S2213671115003161

Similar Items