Dose- and Time-Dependent Effects of Oleate on Mitochondrial Fusion/Fission Proteins and Cell Viability in HepG2 Cells: Comparison with Palmitate Effects

Dose- and Time-Dependent Effects of Oleate on Mitochondrial Fusion/Fission Proteins and Cell Viability in HepG2 Cells: Comparison with Palmitate Effects

Mitochondrial impairments in dynamic behavior (fusion/fission balance) associated with mitochondrial dysfunction play a key role in cell lipotoxicity and lipid-induced metabolic diseases. The present work aimed to evaluate dose- and time-dependent effects of the monounsaturated fatty acid oleate on...

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Bibliographic Details
Main Authors: Isy F. de Sousa, Vincenzo Migliaccio, Marilena Lepretti, Gaetana Paolella, Ilaria Di Gregorio, Ivana Caputo, Eliane Beraldi Ribeiro, Lillà Lionetti
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial dynamics
monounsaturated fatty acids
saturated fatty acids
hepatocytes
cellular adaptation
lipotoxicity
Online Access:https://www.mdpi.com/1422-0067/22/18/9812

Internet

https://www.mdpi.com/1422-0067/22/18/9812

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