Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

DNA three-way junctions are branched structures formed during replication, repair, and recombination, and are involved in models of repeat expansion. Here the authors use single-molecule Förster resonance energy transfer to reveal the dynamics of DNA three-way junctions containing slip-outs composed...

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Bibliographic Details
Main Authors: Tianyu Hu, Michael J. Morten, Steven W. Magennis
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20426-3