Elucidating the Mechanism of Regulation of Transforming Growth Factor β Type II Receptor Expression in Human Lung Cancer Cell Lines

Lung carcinogenesis in humans involves an accumulation of genetic and epigenetic changes that lead to alterations in normal lung epithelium, to in situ carcinoma, and finally to invasive and metastatic cancers. The loss of transforming growth factor β (TGF-β)-induced tumor suppressor function in tu...

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Bibliographic Details
Main Authors: Sunil K. Halder, Yong-Jig Cho, Arunima Datta, Govindaraj Anumanthan, Amy-Joan L. Ham, David P. Carbone, Pran K. Datta
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800795