Knockdown of Bardet-Biedl syndrome gene BBS9/PTHB1 leads to cilia defects.

Knockdown of Bardet-Biedl syndrome gene BBS9/PTHB1 leads to cilia defects.

Bardet-Biedl Syndrome (BBS, MIM#209900) is a genetically heterogeneous disorder with pleiotropic phenotypes that include retinopathy, mental retardation, obesity and renal abnormalities. Of the 15 genes identified so far, seven encode core proteins that form a stable complex called BBSome, which is...

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Bibliographic Details
Main Authors: Shobi Veleri, Kevin Bishop, Damian E Dalle Nogare, Milton A English, Trevor J Foskett, Ajay Chitnis, Raman Sood, Paul Liu, Anand Swaroop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3315532?pdf=render

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http://europepmc.org/articles/PMC3315532?pdf=render

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