In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

Directing nanomedicines to desired locations - such as tumour sites - is difficult to achieve selectively. Here, the authors develop a method to covalently crosslink peptide-modified upconversion nanocrystals into tumour sites for photodynamic therapy and show in vivotumour inhibition in mice.

Bibliographic Details
Main Authors: Xiangzhao Ai, Chris Jun Hui Ho, Junxin Aw, Amalina Binte Ebrahim Attia, Jing Mu, Yu Wang, Xiaoyong Wang, Yong Wang, Xiaogang Liu, Huabing Chen, Mingyuan Gao, Xiaoyuan Chen, Edwin K.L. Yeow, Gang Liu, Malini Olivo, Bengang Xing
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10432

Internet

https://doi.org/10.1038/ncomms10432

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