The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels

The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels

<p>Abstract</p> <p>Background</p> <p>A loss of function of the L-type calcium channel, Cav1.2, results in a cardiac specific disease known as Brugada syndrome. Although many Brugada syndrome channelopathies reduce channel function, one point mutation in the N-terminus o...

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Bibliographic Details
Main Authors: Simms Brett A, Zamponi Gerald W
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Molecular Brain
Subjects:
L-type calcium channel
Beta subunit
Brugada
Channelopathy
Traffic
Cav1.2
Online Access:http://www.molecularbrain.com/content/5/1/9

Internet

http://www.molecularbrain.com/content/5/1/9

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