Catecholamines and Neurodegeneration in Parkinson’s Disease—From Diagnostic Marker to Aggregations of α-Synuclein

Catecholamines and Neurodegeneration in Parkinson’s Disease—From Diagnostic Marker to Aggregations of α-Synuclein

Parkinson’s disease is the second most prevalent disease of the brain. It is characterized by midbrain dopaminergic neuronal degeneration accompanied by Lewy bodies, intra-cytoplasmic neuronal inclusions that consist mainly of alpha-synuclein. The cardinal motor features are muscular rigidity, brady...

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Bibliographic Details
Main Authors: Kenji Yamamoto, Tomoko Oeda, Hideyuki Sawada
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Diagnostics
Subjects:
α-synuclein
aggregation
biomarker
neuroprotection
disease-modifying
Online Access:http://www.mdpi.com/2075-4418/3/2/210

Internet

http://www.mdpi.com/2075-4418/3/2/210

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