The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding RNAs during Vasculogenic Mimicry

In highly metastatic tumors, vasculogenic mimicry (VM) involves the acquisition by tumor cells of endothelial-like traits. Poly-(ADP-ribose) polymerase (PARP) inhibitors are currently used against tumors displaying BRCA1/2-dependent deficient homologous recombination, and they may have antimetastati...

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Bibliographic Details
Main Authors: Mónica Fernández-Cortés, Eduardo Andrés-León, Francisco Javier Oliver
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/12/2690