Dietary omega-3 polyunsaturated fatty acids suppress NHE-1 upregulation in a rabbit model of volume- and pressure-overload

Dietary omega-3 polyunsaturated fatty acids suppress NHE-1 upregulation in a rabbit model of volume- and pressure-overload

Background: Increased consumption of omega-3 polyunsaturated fatty acids (3-PUFAs) from fish oil may have cardioprotective effects during ischemia/reperfusion, hypertrophy, and heart failure (HF). The cardiac Na+/H+-exchanger (NHE-1) is a key mediator for these detrimental cardiac conditions. Conse...

Full description

Bibliographic Details
Main Authors: Marcel evan Borren, Hester M Den Ruijter, Antonius eBaartscheer, Jan Hendrik eRavesloot, Ruben eCoronel, Arie O Verkerk
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Physiology
Subjects:
Heart Failure
Hypertrophy
fish oil
Na/H Exchanger
Poly unsaturated fatty acids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00076/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00076/full

Similar Items