Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages

The yeast Candida albicans is one of the major fungal human pathogens, for which new therapeutic approaches are required. We aimed at enhancements of the phagocytosis efficacy of macrophages by targeting the cell wall structure of C. albicans, as the coverage of the β-glucan layer by mannans is one...

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Bibliographic Details
Main Authors: Shuna Cui, Minghui Li, Rabeay Y. A. Hassan, Anna Heintz-Buschart, Junsong Wang, Ursula Bilitewski
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00016-20