Systemic Bone Density at Disease Onset Is Associated With Joint Erosion Progression in Early Naive to Treatment Rheumatoid Arthritis: A Prospective 12-Month Follow-Up Open-Label Study

Objectives: Osteoporosis and bone erosions are hallmarks of rheumatoid arthritis (RA) since disease onset is underpinned by the inflammatory burden. In this observational study, we aimed to dissect the putative RA-related parameters and bone-derived biomarkers associated with systemic and focal bone...

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Main Authors: Dario Bruno, Anna Laura Fedele, Barbara Tolusso, Angelina Barini, Luca Petricca, Clara Di Mario, Antonella Barini, Luisa Mirone, Gianfranco Ferraccioli, Stefano Alivernini, Elisa Gremese
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.613889/full